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ea0029p1409 | Pituitary Clinical | ICEECE2012

Increased risk of hypothalamic pituitary dysfunction amongst nasopharyngeal cancer survivors with the use of concurrent chemo-irradiation

Ratnasingam J , Karim N , Paramasivam S , Tan Tong Boon A , Vethakkan S , Choong K , Pendek R , Chan S

Background: Radiotherapy is the mainstay of NPC (nasopharyngeal carcinoma) treatment and recently there is increased use of concurrent chemo-irradiation (CCRT) to improve survival. The irradiation field for NPC includes the base of skull, risking radiation damage to the hypothalamic–pituitary (HP) axis.Aims: To evaluate the prevalence of HP dysfunction in NPC survivors post-irradiation and to compare the risk of developing HP dysfunction amongst pat...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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